Bri's paper on Fascin/singed is out in JCB..
He characterised a new phosphorylation site, which is very interesting. The "classical" serine52 is not bundling actin when phosphorylated, and has been described before.
But this one (serine289) is at the tip of filaments when not phosphorylated. Could be interesting to see what happens when both sides are mutated.
Tuesday, 8 May 2012
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