last papers of the year...

a review and a methods paper

ROS and EGFR/Ras signaling in Drosophila immune response

h2o2 rules

wound healing in dolphins

Dolphins often get deep soft-tissue injuries from shark bite, so how does wound healing occur underwater? Apparently, the blubber near the site of the wound undergoes decomposition and releases organohalogens working as antimicrobial substances to clean the wound.

Amazing!

(ref)

hemocytes in the larva are proliferating

Really nice paper from Katja Brückner showing a population of larval hemocytes that proliferate when in touch with the peripheral nervous system in a compartment called epidermal-muscular pockets.
Nice imaging!

reviews

There's a whole issue of Current Opinion in Cell Biology edited by Sonnenberg and Lecuit on cell-cell and ECM adhesion.
Many interesting reviews

spinach fusion RNAs ;)

different subsets of hemocytes in the adult fly

Orthologs

If looking for orthologs (human to flies to zebrafish, or vice versa), Perrimon launched a new site:

http://www.flyrnai.org/cgi-bin/DRSC_orthologs.pl

You input your favorit gene (the CG name for flies, for instance) and you get back the human (or zebrafish) ortholog.
Works really nice.

a nice review on phagocytosis in drosophila by ramet

New RFP balancers

New balancers out. Tubby-RFP on all three chromosomes... A little bit confusing with Tubby on the 2nd or X, but what can you do?

Who will order these?

screen on dorsal closure

paper out on a screen on dorsal closure from Jankovics.

Mainly describes pebble.

role of annexin in membrane repair regulated by calcium

Dev Cell 10th Anniversary Issue

This weeks issue of Dev Cell is a 10th Anniversary Issue with reviews from Wieschaus and Perrimon.

a good review on the role of different cell protrusions during cell migration

new insights on the role of calcium on cadherin mediated-adhesion

Drosophila lymph gland as cancer model

Michele has a "primer" in DMM this week.
A very nice overview of the signaling pathways in the lymph gland..

hydrogen peroxide is important for axon growth upon wound healing

calcium and cadherins in PNAS

hypoxia in hemocytes

a paper that might provide some useful tools for the ROS people

Additional Gene Disruption lines

Bellen et al have released additional gene disruption lines.

You can check their website to see if your favourite gene has now been targeted...

Besides that, a nice paper describing all the different transposons and their use.

‘Model’ or ‘tool’? New definitions for translational research (by H. Sive)

Here is an interesting point of view on what can be named a "disease model" and what shouldn't. The author propose to introduce the distinction between a "model" and a "tool"

Lecuit on RhoGEF2

Lecuit has got a paper in NCB on RhoGEF2...

paper on wound healing in the embryo by parkhurst lab

a veeery detailed analysis on the wound healing process in the embryo, more focused on the function of e-cadherin and plasma membrane dynamics

a nice short review on hemocyte migration

Lymph gland development

A nice paper on lymph gland development. Also looking at the role ECM, but not integrins!

an interesting issue on current topics in dev biol about "Forces and Tension in Development", including one paper by cp heisenberg, one by b. sanson and another by rauzi and francois lenne!

review about drosophila as model system for studying cancer

review on epithelia by Marios and Buzz

There's a nice review from Marios and Buzz on epithelia maintenance and remodeling in JCB this week

quick guide

A quick guide on embryonic hemocytes from the World Wide Wood. Nice and useful introduction

interesting paper on mechanotransduction between the c.elegans epithelium and muscle. involving some new players and a Rac GTPase.

3 secs only

No more than 3 seconds..

p114RhoGEF at cell junctions

Flies in Space

Apparently, if you send flies to space, they descrease their number of hemocytes....

Echinoid

An intersting paper in jcb shows tha echinoid defines the leading edge of dorsal closure.
So the 64 million dollar question,.. wound edge???

role of atypical myosin dachs in regulating cell shape and tissue mechanics and how tension can influence the orientation of the mitotic spindle

paper on the role of sumoylation for the response of the Dros. larvae to the parasitic wasp eggs