nice images

Imaging Course

If anyone is interested in attending an Imaging Course, this is the course to attend!!

 I have never seen such an amazing line-up of speakers...
 The deadline for registration is on the 15th of September although the course is only October next year.

multicolor imaging using two-photon microscopy

paper showing that ecadherin cytoplasmic domain is indeed a molecular sensor for tension (they used a FRET sensor). they also saw that this is dependent on alpha-catenin and actin. and interestingly they found that this force-sensing property of e-cadherin is important not only in cell-cell contacts but also cell contact-free regions.

a review on transcription factors induced by mechanical stress. they talk about interesting molecules for many of us (YAP, NKkappaB, catenins...;)

short review on the piezo proteins

paper showing that H2O2 formed upon injury leads to disruption of epithelial barrier/disassembly of TJs and AJs via Gα12 and Src, both in MDCK cells and mice